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Call your doctor right away if you have any side effects that bother you.

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HOW IMFINZI IS GIVEN

GETTING IMFINZI

If you’re familiar with intravenous (IV) infusions, you may already be comfortable with the routine of an infusion day. Below, you’ll find some information about how IMFINZI is given and some tips that may help you add to your routine–so your treatment days can go as smoothly as possible.

IMFINZI is an Intravenous (IV) Infusion

IMFINZI IS AN INTRAVENOUS (IV) INFUSION

IMFINZI will be given at your doctor’s office or infusion center, so there’s no need for you to pick up IMFINZI from the pharmacy.

Infusion Duration

HOW LONG IS AN INFUSION?

The infusion usually lasts approximately 60 minutes. Your doctor will test your blood to monitor you for certain side effects.

IMFINZI Infusion Dosing Options

INFUSIONS MAY BE GIVEN EITHER EVERY 2 or 4 WEEKS

There are two dosing options to receive your infusion – every 2 weeks or every 4 weeks for up to 12 months. Your doctor will determine how often and how long you will receive IMFINZI. You will stop receiving IMFINZI if your disease progresses or if your side effects are too difficult to manage.

Ask your doctor how long you should stay on IMFINZI. Every person is different. Your doctor will decide how long you will receive IMFINZI and how many treatments you need. He or she will monitor you regularly for possible side effects, and to see if IMFINZI is working to keep your cancer from growing or spreading.

 

Severe infusion reactions. Call or see your healthcare provider right away if you develop any of the following symptoms or if these symptoms get worse. Signs and symptoms may include:

  • Chills or shaking
  • Shortness of breath or wheezing
  • Feeling like passing out
  • Itching or rash
  • Dizziness
  • Back or neck pain
  • Flushing
  • Fever
  • Facial swelling
Reschedule Appointment for IMFINZI Treatment

If you miss any appointments, call your doctor as soon as possible to reschedule.

PREPARING FOR YOUR INFUSION

The more prepared you are, the better your experience will be. Here are a few simple steps you can take that might make your treatment days more comfortable:

Get to the office early to take care of any paperwork.

Don’t forget your insurance card.

If possible, wear comfortable clothing.

Drink Plenty of Water
BEFORE treatment
  • Drink plenty of water
  • Eat a small meal
  • Dress comfortably and in loose-fitting clothing
  • Write down any questions you may have
List of Items to Bring on the IMFINZI treatment Day
DURING treatment

Here are a few things to bring with you that may be useful on treatment day:

  • Identification/insurance card
  • List of medications you are currently taking
  • Activities to keep you occupied, such as reading materials, puzzles, and mobile devices
  • Water bottle and snacks in case you get hungry
  • Lip balm, lotion, and hard candy to help soothe dry skin and lips
  • A sweater or blanket, as it can get cold in the treatment center
Reminder to Schedule Next Appointment for IMFINZI Treatment
AFTER treatment
  • Be sure to schedule your next appointment before leaving the treatment center
  • If possible, take it easy for the rest of the day
Talk to your doctor about IMFINZI
DOWNLOAD THE CONVERSATION GUIDE

NEXT: UNDERSTANDING STAGE 3 NSCLC

Important Safety Information

What is the most important information I should know about IMFINZI® (durvalumab)?

IMFINZI is a medicine that may treat certain cancers by working with your immune system. IMFINZI can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended.

What is IMFINZI?

IMFINZI is a prescription medicine used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC). IMFINZI may be used when your NSCLC has not spread outside your chest, cannot be removed by surgery, and has responded or stabilized with initial treatment with chemotherapy that contains platinum, given at the same time as radiation therapy.

It is not known if IMFINZI is safe and effective in children.

Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:

  • Lung Icon

    Lung problems: cough, shortness of breath, and chest pain

  • Intestine Icon

    Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; and severe stomach-area (abdomen) pain or tenderness

  • Liver Icon

    Liver problems: yellowing of your skin or the whites of your eyes, severe nausea or vomiting, pain on the right side of your stomach area (abdomen), dark urine (tea colored), and bleeding or bruising more easily than normal

  • Hormone Gland Icon

    Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; and changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness

  • Kidney Icon

    Kidney problems: decrease in your amount of urine, blood in your urine, swelling of your ankles, and loss of appetite

  • Skin Irritation Icon

    Skin problems: rash; itching; skin blistering or peeling; painful sores or ulcers in mouth or nose, throat, or genital area; fever or flu-like symptoms; and swollen lymph nodes

  • Pancreas Problems Icon

    Pancreas problems: pain in your upper stomach area (abdomen), severe nausea or vomiting, and loss of appetite

  • Patient with Other Health Issues Icon

    Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with IMFINZI. Call or see your healthcare provider right away for any new or worsening signs or symptoms, which may include: Chest pain, irregular heartbeats, shortness of breath or swelling of ankles; confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems; tingling, numbness or weakness of the arms or legs; double vision, blurry vision, sensitivity to light, eye pain, changes in eye sight; persistent or severe muscle pain or weakness, muscle cramps, joint pain, joint stiffness or swelling; and low red blood cells and bruising

  • Hospital Drips Icon

    Infusion reactions that can sometimes be severe or life-threatening. Signs and symptoms of infusion reactions may include: chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, feel like passing out, fever, and back or neck pain

  • Organ Transplant Complications Icon

    Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with IMFINZI. Your healthcare provider will monitor you for these complications

Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment with IMFINZI. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with IMFINZI if you have severe side effects

Before you receive IMFINZI, tell your healthcare provider about all of your medical conditions, including if you:

  • have immune system problems such as Crohn's disease, ulcerative colitis, or lupus
  • have received an organ transplant
  • have received or plan to receive a stem cell transplant that uses donor stem cells (allogeneic)
  • have received radiation treatment to your chest area
  • have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome
  • are pregnant or plan to become pregnant. IMFINZI can harm your unborn baby

Females who are able to become pregnant:

    • Your healthcare provider will give you a pregnancy test before you start treatment with IMFINZI.
    • You should use an effective method of birth control during your treatment and for 3 months after the last dose of IMFINZI. Talk to your healthcare provider about birth control methods that you can use during this time.
    • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with IMFINZI.
  • are breastfeeding or plan to breastfeed. It is not known if IMFINZI passes into your breast milk. Do not breastfeed during treatment and for 3 months after the last dose of IMFINZI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of IMFINZI?

IMFINZI can cause serious side effects (see above):

The most common side effects of IMFINZI when used alone in adults with non-small cell lung cancer (NSCLC) that cannot be removed by surgery include cough, feeling tired, inflammation in the lungs, upper respiratory tract infections, shortness of breath, and rash.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IMFINZI. Ask your healthcare provider or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects related to AstraZeneca products. If you prefer to report these to the FDA, either visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

What is IMFINZI?

IMFINZI is a prescription medicine used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC). IMFINZI may be used when your NSCLC has not spread outside your chest, cannot be removed by surgery, and has responded or stabilized with initial treatment with chemotherapy that contains platinum, given at the same time as radiation therapy.

It is not known if IMFINZI is safe and effective in children.

Please see Full Prescribing Information including Medication Guide for IMFINZI.

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Important Safety Information +

What is the most important information I should know about IMFINZI® (durvalumab)?

IMFINZI is a medicine that may treat certain cancers by working with your immune system.

What is IMFINZI?

IMFINZI is a prescription medicine used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC). IMFINZI may be used when your NSCLC has not spread outside your chest, cannot be removed by surgery, and has responded or stabilized with initial treatment with chemotherapy that contains platinum, given at the same time as radiation therapy.

It is not known if IMFINZI is safe and effective in children.